Top 4 Benefits of Progesterone

Are you ready to set in for progesterone?

In this emerging area of progesterone research, several research studies attest to the neuroprotective effects of progesterone, an absence of neurological side effects, and a benefit for cognitive function.
Progesterone as a "neurosteroid"
Progesterone has been classified as a "neurosteroid". It is so essential that it comes from two different places to reach the brain; first, cells in the brain, spinal cord, and peripheral nervous system all synthesise progesterone from cholesterol. Secondly, progesterone that is circulating in the bloodstream also has direct access to the brain and nerves. Important role of progesterone is to protect the brain from damage and repair after injury. It actually does this by promoting the growth and repair of the myelin sheath that protects the nerve fibres.
Progesterone naturally metabolises in brain tissues to the metabolite allopregnanolone, which is known to produce calming, anti-anxiety and possibly enhanced memory effects. There is some speculation that it could be important in preserving cognitive function in women experiencing the decline in progesterone level with age. However, it's important to note that progesterone is produced by brain tissue itself, and so the reduction in blood progesterone levels as ovarian production decreases may be as important as other raging processes that have direct effects on the brain's function.
Progesterone that could also affect the brain development for smarter kids?
There is published evidence that the children of women who were treated with progesterone during pregnancy showed enhanced development during infancy, achieved better academic results at ages 9-10, and were significantly more likely to attend universities. The observed benefits can be explained by the fact that it is essential for optimal development of a normal brain in the foetus. If progesterone levels are too low, normal brain development may be affected, putting an infant at a developmental disadvantage.
Progesterone as sleeping aid?
Women using an oral progesterone may notice a sedative effect, and doctors usually recommend that the oral form is taken at bedtime. Basically, there is a  large quantity of metabolites produced in the liver after oral progesterone is absorbed by the intestines. These metabolites have known sedative and hypnotic effects. On the other hand, women using progesterone cream do not produce metabolites in such large quantities because the progesterone is absorbed through the skin and by passes the liver metabolism. However, as stated before, some women may experience progesterone's calming effect after using it in cream form
Progestins VS Progesterone 
Synthetic progestins are molecularly different from natural progesterone and therefore do not metabolite to the same compounds as natural progesterone. They do not show benefits for cognitive or anti-anxiety function. In fact, they have not been found to have any of progesterone's neuroprotective properties. The progestin that has been the most extensively studies and which is commonly used in synthetic hormone replacement therapy, MPA (medroxyprogesterone acetate), has been found to have negative effects on the nervous system and even reduces the beneficial effects of estrogen.
@Women in Balance Institute